Here's the shocking way 'Grey's Anatomy' said goodbye to Dr. Alex Karev (2024)

Warning! This story contains spoilers for the March 5 episode of "Grey's Anatomy."

In some ways, Thursday night's episode of "Grey's Anatomy" turned out to be exactly what fans expected.

After all, they've known for a long time that Dr. Alex Karev has not wanted to return to the halls of Gray Sloan Memorial Hospital since the actorJustin Chambers announced his decision to leave the hit series after 15 yearsback in January.

And fans also know that any ending to "Grey's Anatomy" is sure to be a surprise.

But that's where all expectations ended on Thursday, as viewers couldn't possibly have seen itthis is coming.

As Bailey (Chandra Wilson) revealed, the good doctor — who was one of the original interns back in the days of Seattle Grace — didn't just quit his job.

“Alex Karev isn't coming back,” she said, holding a letter from him. "Left his wife, his friends, his job..."

Yes, bombshell number 1 is that Alex has dumped Jo (Camilla Luddington), who he married just two years ago. But get ready for number 2!

“Alex Karev is now a father of two… with Izzie Stevens,” Bailey continued.

Never before have so few words caused so much shock.

Here's the shocking way 'Grey's Anatomy' said goodbye to Dr. Alex Karev (1)

But the chief of operations wasn't the only one to receive a letter full of juicy details. Meredith (Ellen Pompeo), Jo, and Richard (James Pickens Jr.) also received letters, and they all shed light on Alex's apparent deviant character.

It all harkened back to events from earlier in season 16, including Meredith's big lawsuit to keep her medical license — an event that led Alex to reach out to old associates on her behalf, even his ex-wife, Izzie, from who he discovered started her. a family with embryos that they had frozen during their marriage. So suddenly he was the father of 5-year-old twins.

And apparently that's all it took to change my mind about everything. Or, as he put it in his letter to Jo: "When I told you I loved you, I meant it, but Izzie has our children, Jo."

Van.

That expression of pain is not only on behalf of Jo, but also on behalf of all loyalists'Grey's' lovers who are spoiled by Alex's departure.

There were many ways@GreysABCcould have written the end of Alex Karev. Leaving Jo for another woman, let alone Izzie, wasn't one of them. I've never hated an episode as much as this one and there have been 356 of them.#Grey's anatomie https://t.co/x4vEXVVwCM

— Cindy (@cschlorf07)March 6, 2020

As if George O'Malley getting hit by a bus, Lexie and Mark dying, Cristina Yang going to Switzerland, Derek getting hit by a car, Callie Torres leaving, April and Arizona leaving the show wasn't enough, they had to get the worst ending for Alex Karev.
me at the moment::#Grey's anatomie pic.twitter.com/ejnNXSpCT7

— ardentdreamer08 (@ardentdreamer08)March 6, 2020

Alex, suddenly going back to Izzie, was righteousa plot point for far too many people, who indicated that they would have preferred to see himkilledthen to leave as he did.

#Grey's anatomieIf Alex gets hit by a truck, it would hurt less

— lauradaniels (@lauradan81)March 6, 2020

I'm going to forget I ever saw this episode and tell myself that Alex has died.#Grey's anatomie pic.twitter.com/UeJdX769lD

— Christalyn S (@Christalyn13)March 6, 2020

me: They better NOT KILL ALEX, I swear

me this week: ......they should have just killed him......#Grey's anatomie pic.twitter.com/Z8NCN4PY3A

— Harshal (@iHarshalWatts)March 6, 2020

Some even went so farwrite their own conclusion in that direction.

I have concluded that Alex Karev died on the way to his mother and that his body was never claimed. End.#Grey's anatomie pic.twitter.com/TGmXBZn7bL

— Chart (@DCalyne)March 6, 2020

A person whodeedDo you appreciate Alex's farewell? Pompeo, the star of the show.

“For me personally, Karev was going back to the beginning… the best possible story,” she wrote in oneposts on InstagramFriday. “It's a tribute to the incredible early years and the incredible cast... who created a foundation so strong that the show still stands today.”

But fortunately or not, it's really over.

“There is no good time to say goodbye to a show and a character that has defined so much of my life over the past 15 years,” the star says.Chambers said in a statement to TODAYwhen he first announced his departure. "However, I have been hoping to diversify my acting roles and career choices for some time now. And now that I'm turning 50 and blessed with a remarkable, supportive wife and five wonderful children, now is the time."

And Alex is blessed with surprise twins and... Izzie?

Rie Hines

Ree Hines is a freelance writer and editor covering pop culture, lifestyle stories and trending news. She is also a soul music-loving, coffee-obsessed member of both Team Cat and Team Dog. Ree lives in Tampa, Florida and is a regular contributor to TODAY.com.

Here's the shocking way 'Grey's Anatomy' said goodbye to Dr. Alex Karev (2024)

FAQs

Why did Alex Karev suddenly leave GREY's anatomy? ›

"For some time now, I have hoped to diversify my acting roles and career choices," Chambers said in a 2020 interview with Deadline. Alex had started as a mere intern and moved all the way up to a pediatric surgical fellow, so it's possible Chambers felt he had taken the character as far as he could.

What was the last scene Alex Karev was in? ›

After brief exchange on the phone, Alex says he heard little voices in the background and asked if Izzie had kids and after a silence, she revealed that she did. And it turns out they are his children. Alex Karev's (Justin Chambers) last physical appearance includes this scene in the 350th episode "My Shot".

Will Alex Karev ever come back? ›

Us Weekly can confirm that Chambers is not set for a return to the show. Chambers announced in January 2020 that he would no longer be playing Dr. Alex Karev after 16 seasons on the ABC medical drama.

Who is the richest Grey's Anatomy cast? ›

Ellen Pompeo has made some serious bank from her nearly two decade long run as the titular character Grey's Anatomy. The actress has reportedly made a whopping $U80 million (approx. $123.3 million) from the series. Pompeo was even listed on Forbes' highest earning actress list in 2020.

Do Alex and Jo get married? ›

She spirals into a deep depression. In the finale "Jump into the Fog", Jo voluntarily checks into the psych ward. In the sixteenth season, Jo emerges from the psych ward, and she and Alex get legally married, after finding out they never signed a marriage license. She also becomes an attending.

What happens to Jo after Alex leaves? ›

Following Alex's departure, and after a couple of obstacles in the adoption process, Jo became the mother of Luna, a baby whose mother died in childbirth, and started a new life with her.

Why did Jo and Alex divorce? ›

Following her estranged husband's death, she married Alex Karev until he left her for his ex-wife, Izzie.

Who is Justin Chambers married to now? ›

While the "Grey's Anatomy" alum is generally quiet when it comes to his private life, he gave a heartwarming look at what it's like being a dad to four girls: Isabella, 29, Maya and Kaila, 26 and Eva, 24, who he shares with wife Keisha Chambers.

What did Alex's letter to Meredith say? ›

Mer, this is not the way I wanted to do this, but you know me,” Karev said in the letter. “Any chance to take the easy way out. You know as well as I do, you'd yell or give me guilt or crap or whatever you do that seems to always set me straight. You were always the one to set me straight.

Who did Karev end up with? ›

In season 9, Karev befriends intern Jo Wilson. They begin a relationship in season 10 until their break-up in the season 12. However, they get back together again and marry in season 14. Karev later leaves Jo and gets back together with his ex-wife Izzie Stevens in season 16.

Did Izzie Stevens come back? ›

Izzie's time with cancer was rough, and it took a toll on her relationship with Alex. After she was fired from SGMW, she left Alex. Eventually, she did come back, wanting to reunite with Alex when she found out her cancer was gone.

Does Alex come back to Grey's Anatomy season 20? ›

Jessica Capshaw is set to guest star in Season 20 of Grey's Anatomy, reprising her beloved role as Dr. Arizona Robbins. Also Alex Landi will return as Dr. Nico Kim.

Is Callie Rich in Grey's Anatomy? ›

Callie comes from a wealthy family, although she's not always forthcoming with those details since she wants to forge her own path without help from her parents.

What happens to Link and Amelia? ›

They divorce early in the fourteenth season civilly, after Amelia's brain tumor is removed, explaining some of her erratic behavior late in the thirteenth season.

How much did Yang make on GREY's anatomy? ›

Sandra Oh (Cristina Yang)

It's unclear what she made at the time, but in 2012, around the time of season 9, TV Guide, reported that Oh made $350,000 per episode, which was the same amount that Dempsey and Pompeo made at the time. According to Celebrity Net Worth, she's worth $25 million.

Why wasn t Alex Karev in the last episode? ›

Because Chambers filmed his last episode for the series in November of last year, Karev did not make an appearance during the episode (though the actor did provide voiceover for letters Karev wrote Jo and his friends that explained why he left).

Why did April Kepner leave Grey's Anatomy? ›

In the season finale, April and Matthew get married. She resigns from the hospital to provide much-needed medical care for the homeless communities in Seattle, something she and Matthew had been doing together on a voluntary basis.

Who replaced Alex Karev in GREY's anatomy? ›

Richard Flood has been cast in 'Grey's Anatomy' as head of Paediatric Surgery, replacing the recently fired Alex Karev (Justin Chambers).

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